LRRN2

Across TCGA cell cohorts, LRRN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,806 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible LRRN2-associated GO terms across cancer lineages are Nucleic acid catabolic process, Regulation of transcription initiation by RNA polymerase II, and RNA catabolic process. Each is linked with LRRN2 in more than 11 cancer types. Because this analysis shows association rather than direction, both LRRN2-to-partner and partner-to-LRRN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid catabolic process grouped by LRRN2-low versus LRRN2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN2→partner) and Y-score (partner→LRRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Nucleic acid catabolic process →	+0.061	+1.347	<.001	.002	3	12
PANCREAS	Regulation of transcription initiation by RNA polymerase II →	+0.068	+0.625	<.001	<.001	3	11
STOMACH	RNA catabolic process →	+0.066	+1.650	<.001	.003	2	12
STOMACH	mRNA catabolic process →	+0.049	+1.102	<.001	.001	3	11
BLOOD_Leukemia	Regulation of nucleotide-excision repair →	+0.107	+0.993	<.001	<.001	3	10
STOMACH	Cytoplasmic translation →	+0.111	+1.703	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,806 associations by consensus.

Nucleic acid catabolic process by LRRN2 expression — STOMACH

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