LRRN1

Across TCGA patient cohorts, LRRN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,294 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRN1-associated proteins across cancer lineages are SETMAR, RIOK3, and PDS5B. Each is linked with LRRN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRN1-to-partner and partner-to-LRRN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRN1 versus SETMAR in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN1→partner) and Y-score (partner→LRRN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SETMAR →	+0.325	+1.314	<.001	<.001	3	5
LSCC	RIOK3 →	-0.282	-0.786	.001	.008	3	4
GBM	PDS5B →	+0.425	+1.629	<.001	<.001	3	4
PDAC	VCL →	+0.354	+1.294	<.001	<.001	3	4
OV	SVIL →	+0.361	+1.310	.001	.003	3	4
GBM	TOP2B →	+0.463	+1.536	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,294 associations by consensus.

LRRN1 vs SETMAR — GBM

Explore this scatter interactively →