LRRN1

Across TCGA cell cohorts, LRRN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,805 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRRN1-associated GO terms across cancer lineages are Chromosomal 5-methylcytosine DNA demethylation pathway, Internal protein amino acid acetylation, and Nucleic acid catabolic process. Each is linked with LRRN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRRN1-to-partner and partner-to-LRRN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal 5-methylcytosine DNA demethylation pathway grouped by LRRN1-low versus LRRN1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRN1→partner) and Y-score (partner→LRRN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.176	+2.196	<.001	<.001	3	7
LUNG_SCLC	Internal protein amino acid acetylation →	+0.167	+1.794	<.001	<.001	3	7
SOFT_TISSUE	Nucleic acid catabolic process →	+0.057	+2.093	<.001	.003	3	6
OVARY	Regulation of organelle assembly →	+0.030	+1.515	.006	.009	2	7
SOFT_TISSUE	Negative regulation of mRNA catabolic process →	+0.112	+3.161	<.001	<.001	3	6
LUNG_SCLC	Regulation of cell cycle G1/S phase transition →	+0.083	+2.361	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,805 associations by consensus.

Chromosomal 5-methylcytosine DNA demethylation pathway by LRRN1 expression — LUNG_SCLC

Explore this box plot interactively →