Across TCGA patient cohorts, LRRIQ4 protein abundance is significantly associated with the RNA expression of many other genes, with 91 significant associations in total. COAD shows the largest number of these associations.

The most reproducible LRRIQ4-associated genes across cancer lineages are ANKRD54, COG4, and AXIN1. Each is linked with LRRIQ4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRIQ4-to-partner and partner-to-LRRIQ4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRIQ4→partner) and Y-score (partner→LRRIQ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ANKRD54 →	+0.510	+1.076	.004	<.001	3	1
COAD	COG4 →	+0.707	+1.479	.003	.001	3	1
COAD	AXIN1 →	+0.636	+0.901	.002	.008	3	1
COAD	POMT1 →	+0.454	+1.047	.005	.001	3	1
COAD	CHMP1A →	+0.529	+1.280	<.001	<.001	3	1
COAD	CNMD →	+0.078	+1.145	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

Exploration

LRRIQ4 survival (RNA) · tumor vs normal (RNA) · all LRRIQ4 data types