Across TCGA cell cohorts, LRRIQ4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,648 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LRRIQ4-associated GO terms across cancer lineages are Hyperosmotic salinity response, Cellular hyperosmotic salinity response, and Adenosine catabolic process. Each is linked with LRRIQ4 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRIQ4-to-partner and partner-to-LRRIQ4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRIQ4→partner) and Y-score (partner→LRRIQ4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Hyperosmotic salinity response →	-0.189	-0.230	.001	.003	3	6
LARGE_INTESTINE	Cellular hyperosmotic salinity response →	-0.189	-0.230	.001	.003	3	6
LUNG_NSCLC_LUAD	Adenosine catabolic process →	-0.793	-0.289	<.001	.004	3	5
LARGE_INTESTINE	Negative regulation of cell fate commitment →	-0.364	-0.248	.001	.003	3	5
URINARY_TRACT	Negative regulation of T-helper 17 cell lineage commitment →	-0.428	-0.256	<.001	.002	3	5
LUNG_SCLC	Multivesicular body organization →	+0.059	+0.744	.009	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,648 associations by consensus.

Exploration

LRRIQ4 survival (RNA) · tumor vs normal (RNA) · all LRRIQ4 data types