LRRIQ3

Across TCGA patient cohorts, LRRIQ3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,132 significant associations in total. THCA shows the largest number of these associations.

The most reproducible LRRIQ3-associated GO terms across cancer lineages are Intraciliary transport, Transport along microtubule, and Non-motile cilium assembly. Each is linked with LRRIQ3 in more than 32 cancer types. Because this analysis shows association rather than direction, both LRRIQ3-to-partner and partner-to-LRRIQ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport grouped by LRRIQ3-low versus LRRIQ3-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRIQ3→partner) and Y-score (partner→LRRIQ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Intraciliary transport →	+0.060	+0.506	.002	.001	2	33
ESCA	Transport along microtubule →	+0.039	+0.220	<.001	<.001	3	30
SCLC	Non-motile cilium assembly →	+0.058	+0.591	.003	.004	1	31
ESCA	Protein quality control for misfolded or incompletely synthesized proteins →	+0.046	+0.235	<.001	<.001	3	29
STAD	Obsolete mRNA methylation →	+0.060	+0.147	<.001	<.001	3	28
SCLC	Protein localization to ciliary membrane →	+0.091	+0.483	.002	.005	1	30

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,132 associations by consensus.

Intraciliary transport by LRRIQ3 expression — SCLC

Explore this box plot interactively →