LRRFIP1P1

Across TCGA patient cohorts, LRRFIP1P1 mutation is significantly associated with the RNA expression of many other genes, with 3,594 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRFIP1P1-associated genes across cancer lineages are RNA5SP413, RNA5SP412, and SS18L2P1. Each is linked with LRRFIP1P1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRRFIP1P1-to-partner and partner-to-LRRFIP1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by LRRFIP1P1-low versus LRRFIP1P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRFIP1P1→partner) and Y-score (partner→LRRFIP1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+1.136	+1.746	<.001	.006	3	3
UCEC	RNA5SP412 →	+0.646	+2.159	<.001	.001	3	3
CESC	SS18L2P1 →	+0.255	+5.306	<.001	.006	3	2
CESC	PPP1R1AP2 →	+0.247	+6.837	<.001	<.001	3	2
UCEC	LINC01072 →	+0.116	+2.073	<.001	.005	3	2
UCEC	RNA5SP418 →	+0.812	+2.055	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,594 associations by consensus.

RNA5SP413 by LRRFIP1P1 expression — UCEC

Explore this box plot interactively →