LRRFIP1

Across TCGA pan-cancer cohorts, LRRFIP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LRRFIP1 data layer compared with 20 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LRRFIP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LRRFIP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, CCRCC, and PDAC are the cancer types where LRRFIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	1.000	0.833	.009	32	view →
CCRCC	OS	Median	All	0.752	0.920	.005	24	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
GBM	DFS	Tertile	All	0.273	0.460	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

LRRFIP1–UCEC (DFS)

Open the UCEC breakdown →