LRRFIP1

Across TCGA cell cohorts, LRRFIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,654 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRFIP1-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Negative regulation of cilium assembly, and Positive regulation of plasma membrane repair. Each is linked with LRRFIP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both LRRFIP1-to-partner and partner-to-LRRFIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by LRRFIP1-low versus LRRFIP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRFIP1→partner) and Y-score (partner→LRRFIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol biosynthetic process →	+0.068	+0.979	<.001	<.001	3	12
BLOOD_Leukemia	Negative regulation of cilium assembly →	+0.070	+1.105	<.001	<.001	3	11
BONE	Positive regulation of plasma membrane repair →	+0.238	+0.946	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.050	+0.872	<.001	<.001	3	11
BONE	Negative regulation of small GTPase mediated signal transduction →	+0.112	+1.443	<.001	<.001	3	11
BREAST	Endocytic recycling →	+0.059	+0.927	.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,654 associations by consensus.

Phosphatidylinositol biosynthetic process by LRRFIP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →