LRRFIP1

Across TCGA cell cohorts, LRRFIP1 mutation is significantly associated with the drug of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LRRFIP1-associated genes across cancer lineages are SGC-CBP30, AGI-6780, and GSK3337463A. Each is linked with LRRFIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRFIP1-to-partner and partner-to-LRRFIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SGC-CBP30 grouped by LRRFIP1-low versus LRRFIP1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRFIP1→partner) and Y-score (partner→LRRFIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SGC-CBP30 →	+0.303	+2.649	.032	.046	3	1
LARGE_INTESTINE	AGI-6780 →	+0.406	+2.646	.036	.047	3	1
LARGE_INTESTINE	GSK3337463A →	+0.374	+2.649	.028	.046	3	1
LARGE_INTESTINE	IC-87114 →	+0.256	+2.652	.012	.045	3	1
LARGE_INTESTINE	WYE-125132 →	+0.663	+2.652	.008	.045	3	1
LARGE_INTESTINE	Tenovin-6 →	+0.424	+2.786	.039	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

SGC-CBP30 by LRRFIP1 expression — LARGE_INTESTINE

Explore this box plot interactively →