LRRCC1

Across TCGA pan-cancer cohorts, LRRCC1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LRRCC1 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher LRRCC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRCC1 expression acts as an unfavorable survival marker.

GBM and LUAD are the cancer types where LRRCC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Median	All	0.263	0.491	.005	3	view →
LUAD	OS	Quartile	III,IV	0.303	0.739	.016	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

LRRCC1–GBM (DFS)

Open the GBM breakdown →