LRRCC1

Across TCGA cell cohorts, LRRCC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,702 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LRRCC1-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, DNA replication, and Double-strand break repair. Each is linked with LRRCC1 in more than 15 cancer types. Because this analysis shows association rather than direction, both LRRCC1-to-partner and partner-to-LRRCC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by LRRCC1-low versus LRRCC1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRCC1→partner) and Y-score (partner→LRRCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.084	+0.914	<.001	<.001	3	16
BLOOD_Myeloma	DNA replication →	+0.106	+1.252	<.001	.005	2	16
LUNG_SCLC	Double-strand break repair →	+0.062	+1.393	<.001	<.001	3	15
OVARY	Replication fork processing →	+0.097	+1.490	<.001	<.001	3	15
LUNG_SCLC	Double-strand break repair via homologous recombination →	+0.074	+1.235	<.001	<.001	3	14
LUNG_SCLC	Recombinational repair →	+0.077	+1.180	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,702 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by LRRCC1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →