LRRC9

Across TCGA patient cohorts, LRRC9 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,182 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRRC9-associated proteins across cancer lineages are PHF14, DDX42, and RPRD1B. Each is linked with LRRC9 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRC9-to-partner and partner-to-LRRC9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC9 versus PHF14 in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC9→partner) and Y-score (partner→LRRC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PHF14 →	+0.362	+0.467	<.001	<.001	3	4
LSCC	DDX42 →	+0.245	+0.495	<.001	<.001	3	4
OV	RPRD1B →	+0.291	+0.359	.004	.008	2	5
LSCC	SMARCC2 →	+0.202	+0.378	<.001	<.001	3	4
OV	BRD3 →	+0.212	+0.304	.003	.005	3	4
LUAD	APEH_S187 →	-0.330	-0.290	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,182 associations by consensus.

LRRC9 vs PHF14 — LSCC

Explore this scatter interactively →