LRRC9

Across TCGA patient cohorts, LRRC9 protein abundance is significantly associated with the RNA expression of many other genes, with 175 significant associations in total. OV shows the largest number of these associations.

The most reproducible LRRC9-associated genes across cancer lineages are ST13, PQBP1, and KCNA7. Each is linked with LRRC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC9-to-partner and partner-to-LRRC9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC9 versus ST13 in OV, with a Pearson correlation of 0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC9→partner) and Y-score (partner→LRRC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ST13 →	+0.895	+0.454	.007	.001	3	1
OV	PQBP1 →	+0.802	+0.442	.001	.001	3	1
OV	KCNA7 →	-0.105	-0.368	<.001	<.001	3	1
OV	RPS6KB1 →	+0.660	+0.368	.002	<.001	3	1
OV	PEX12 →	+1.020	+0.368	<.001	<.001	3	1
OV	RAB35 →	+1.030	+0.382	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 175 associations by consensus.

LRRC9 vs ST13 — OV

Explore this scatter interactively →