LRRC9

Across TCGA cell cohorts, LRRC9 RNA expression is significantly associated with the RNA expression of many other genes, with 3,486 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LRRC9-associated genes across cancer lineages are HTR2C, PLCB1, and H2BW2. Each is linked with LRRC9 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRRC9-to-partner and partner-to-LRRC9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC9 versus HTR2C in OESOPHAGUS, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC9→partner) and Y-score (partner→LRRC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	HTR2C →	+0.831	+0.135	<.001	<.001	3	3
LIVER	PLCB1 →	+2.244	+0.225	<.001	.001	3	3
OVARY	H2BW2 →	+0.119	+0.060	<.001	<.001	3	3
LUNG_SCLC	RASGEF1B →	+2.946	+1.104	<.001	<.001	3	3
CNS	UNC45B →	+0.157	+0.081	.002	<.001	3	2
LUNG_NSCLC_LUAD	MCHR2 →	+0.035	+0.048	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,486 associations by consensus.

LRRC9 vs HTR2C — OESOPHAGUS

Explore this scatter interactively →