LRRC9

Across TCGA cell cohorts, LRRC9 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,679 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible LRRC9-associated GO terms across cancer lineages are Calcium ion transport, Positive regulation of mRNA metabolic process, and mRNA destabilization. Each is linked with LRRC9 in more than 7 cancer types. Because this analysis shows association rather than direction, both LRRC9-to-partner and partner-to-LRRC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium ion transport grouped by LRRC9-low versus LRRC9-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC9→partner) and Y-score (partner→LRRC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Calcium ion transport →	-0.041	-0.082	<.001	.005	3	8
OESOPHAGUS	Positive regulation of mRNA metabolic process →	+0.058	+0.129	<.001	.001	3	7
OESOPHAGUS	mRNA destabilization →	+0.075	+0.160	<.001	.002	3	6
LUNG_SCLC	Protein modification by small protein removal →	+0.057	+0.987	<.001	.001	3	6
OESOPHAGUS	Membrane fission →	+0.089	+0.188	<.001	.003	3	6
BREAST	Intracellular calcium ion homeostasis →	-0.043	-0.077	.004	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,679 associations by consensus.

Calcium ion transport by LRRC9 expression — BLOOD_Leukemia

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