LRRC77P

Across TCGA patient cohorts, LRRC77P mutation is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible LRRC77P-associated genes across cancer lineages are RFPL4AP7, MIR8054, and RNU1-17P. Each is linked with LRRC77P in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC77P-to-partner and partner-to-LRRC77P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFPL4AP7 grouped by LRRC77P-low versus LRRC77P-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC77P→partner) and Y-score (partner→LRRC77P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RFPL4AP7 →	+0.689	+5.068	<.001	.008	3	2
ESCA	MIR8054 →	+0.668	+5.450	<.001	.004	3	2
ESCA	RNU1-17P →	+0.772	+5.068	<.001	.008	3	2
UCEC	RN7SKP46 →	+0.198	+5.736	<.001	.001	3	2
UCEC	RNU6-871P →	+0.442	+4.453	<.001	.006	3	2
ESCA	RNU6-956P →	+0.423	+5.450	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

RFPL4AP7 by LRRC77P expression — ESCA

Explore this box plot interactively →