Across TCGA pan-cancer cohorts, LRRC72 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LRRC72’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LRRC72 RNA is repressed in tumor relative to normal tissue. In most cancer types LRRC72 is over-expressed in tumor, although a few such as KICH and COAD show the opposite, repressed pattern.

KICH, HNSC, and COAD are the cancer types where LRRC72 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LRRC72 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.019	.012	3	view →
HNSC	Male	IV	+0.043	.038	2	view →
COAD	Male	II,III,IV	−0.014	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: LRRC72 RNA expression & survival · all LRRC72 data types