LRRC7-AS1

Across TCGA pan-cancer cohorts, LRRC7-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LRRC7-AS1 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher LRRC7-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LRRC7-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

CESC, KIRC, and BRCA are the cancer types where LRRC7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	All	0.242	0.798	.004	72	view →
KIRC	DFS	Tertile	All	0.711	0.596	.008	61	view →
BRCA	OS	Tertile	All	0.785	0.927	<.001	48	view →
SKCM	DFS	Tertile	III,IV	0.066	0.616	<.001	48	view →
THCA	DFS	Tertile	III,IV	0.182	0.703	.005	42	view →
UCS	OS	Tertile	II,III,IV	0.007	0.616	<.001	36	view →
LIHC	DFS	Tertile	All	0.234	0.548	.003	27	view →
LGG	DFS	Median	All	0.879	0.786	.001	21	view →
LUAD	DFS	Tertile	IV	0.333	0.671	.048	18	view →
PCPG	DFS	Tertile	All	0.535	0.936	.001	18	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
TGCT	OS	Tertile	II,III,IV	0.802	1.000	.040	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LRRC7-AS1–CESC (OS)

Open the CESC breakdown →