Across TCGA cell cohorts, LRRC66 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,164 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LRRC66-associated GO terms across cancer lineages are Vacuole organization, Macroautophagy, and Golgi ribbon formation. Each is linked with LRRC66 in more than 8 cancer types. Because this analysis shows association rather than direction, both LRRC66-to-partner and partner-to-LRRC66 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC66→partner) and Y-score (partner→LRRC66) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Vacuole organization →	+0.045	+0.262	<.001	<.001	3	9
BLOOD_Myeloma	Macroautophagy →	+0.048	+0.328	.001	.002	3	9
BONE	Golgi ribbon formation →	+0.098	+0.423	<.001	<.001	3	8
SKIN	Positive regulation of cell-substrate junction organization →	+0.070	+0.204	.004	.002	3	8
LUNG_NSCLC_LUAD	Cortical actin cytoskeleton organization →	+0.055	+0.192	<.001	<.001	3	8
KIDNEY	Regulation of stress-activated MAPK cascade →	+0.093	+0.220	.003	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,164 associations by consensus.

Exploration

LRRC66 survival (RNA) · tumor vs normal (RNA) · all LRRC66 data types