LRRC6

Across TCGA patient cohorts, LRRC6 protein abundance is significantly associated with the RNA expression of many other genes, with 1,917 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC6-associated genes across cancer lineages are RSPH14, RAB36, and DNAL4. Each is linked with LRRC6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC6-to-partner and partner-to-LRRC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC6 versus RSPH14 in UCEC, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC6→partner) and Y-score (partner→LRRC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RSPH14 →	+1.425	+1.011	<.001	<.001	3	1
UCEC	RAB36 →	+1.542	+1.182	<.001	<.001	3	1
UCEC	DNAL4 →	+1.441	+1.132	<.001	.002	3	1
UCEC	IFT27 →	+0.955	+1.030	<.001	<.001	3	1
UCEC	CDKN3 →	-1.140	-1.128	.003	.001	3	1
UCEC	SAMD15 →	+2.006	+1.397	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,917 associations by consensus.

LRRC6 vs RSPH14 — UCEC

Explore this scatter interactively →