LRRC6

Across TCGA cell cohorts, LRRC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,310 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRRC6-associated GO terms across cancer lineages are Regulation of myoblast fusion, Regulation of syncytium formation by plasma membrane fusion, and Striated muscle contraction. Each is linked with LRRC6 in more than 10 cancer types. Because this analysis shows association rather than direction, both LRRC6-to-partner and partner-to-LRRC6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by LRRC6-low versus LRRC6-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC6→partner) and Y-score (partner→LRRC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.077	+0.326	<.001	<.001	3	11
BLOOD_Lymphoma	Regulation of syncytium formation by plasma membrane fusion →	+0.084	+0.342	.001	.001	3	9
SOFT_TISSUE	Striated muscle contraction →	+0.080	+1.217	.002	<.001	3	9
LUNG_NSCLC_LUSC	Macroautophagy →	+0.080	+1.437	.002	.004	3	9
STOMACH	Regulation of TOR signaling →	+0.071	+1.144	.003	.003	3	9
CNS	Cilium-dependent cell motility →	-0.068	-1.199	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,310 associations by consensus.

Regulation of myoblast fusion by LRRC6 expression — BLOOD_Lymphoma

Explore this box plot interactively →