LRRC57P1

Across TCGA pan-cancer cohorts, LRRC57P1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LRRC57P1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher LRRC57P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRC57P1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

KIRP, THCA, and STAD are the cancer types where LRRC57P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.772	0.934	.001	72	view →
THCA	OS	Tertile	III,IV	0.171	0.788	<.001	39	view →
STAD	DFS	Tertile	All	0.379	0.725	.001	21	view →
CESC	DFS	Tertile	IV	0.053	0.529	<.001	18	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	18	view →
KIRC	DFS	Tertile	IV	0.111	0.650	<.001	18	view →
LUAD	DFS	Tertile	All	0.618	0.781	.007	18	view →
HNSC	DFS	Tertile	IV	0.795	0.556	.039	18	view →
CHOL	DFS	Tertile	All	0.109	0.515	.015	9	view →
BRCA	DFS	Quartile	IV	0.595	0.211	.015	9	view →
BLCA	DFS	Tertile	IV	0.178	0.488	.011	9	view →
LIHC	OS	Tertile	All	0.302	0.680	.043	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LRRC57P1–KIRP (DFS)

Open the KIRP breakdown →