LRRC56

Across TCGA patient cohorts, LRRC56 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,168 significant associations in total. THCA shows the largest number of these associations.

The most reproducible LRRC56-associated GO terms across cancer lineages are Extracellular transport, Axoneme assembly, and Depyrimidination. Each is linked with LRRC56 in more than 23 cancer types. Because this analysis shows association rather than direction, both LRRC56-to-partner and partner-to-LRRC56 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Extracellular transport grouped by LRRC56-low versus LRRC56-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC56→partner) and Y-score (partner→LRRC56) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Extracellular transport →	+0.075	+0.925	<.001	<.001	3	24
UCEC	Axoneme assembly →	+0.084	+0.993	<.001	<.001	3	24
KIRP	Depyrimidination →	+0.058	+1.074	<.001	<.001	3	24
GBM	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.059	+0.723	<.001	<.001	3	24
GBM	Base-excision repair, gap-filling →	+0.042	+0.540	<.001	<.001	3	23
SCLC	Positive regulation of DNA repair →	+0.055	+0.771	.002	.002	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,168 associations by consensus.

Extracellular transport by LRRC56 expression — UCEC

Explore this box plot interactively →