Across TCGA pan-cancer cohorts, LRRC55 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LRRC55 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher LRRC55 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LRRC55 expression acts as an unfavorable survival marker.

SCLC and MESO are the cancer types where LRRC55 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	II,III,IV	0.082	0.702	<.001	24	view →
MESO	OS	Median	II,III,IV	0.130	0.571	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: LRRC55 tumor-vs-normal RNA expression · all LRRC55 data types