LRRC55

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC55 mutation is significantly associated with the RNA expression of many other genes, with 2,378 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC55-associated genes across cancer lineages are CA15P2, MIR4510, and MYO19. Each is linked with LRRC55 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC55-to-partner and partner-to-LRRC55 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC55→partner) and Y-score (partner→LRRC55) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCCA15P2 →+0.043+5.758.007.00332
CESCMIR4510 →+0.238+4.757<.001.00432
SKCMMYO19 →+0.466+2.031<.001<.00132
SKCMABALON →+0.563+2.647<.001<.00132
SKCMTSPY26P →-0.838-2.302<.001<.00132
SKCMELOA-AS1 →+0.348+1.478.005.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,378 associations by consensus.

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