LRRC52-AS1

Across TCGA pan-cancer cohorts, LRRC52-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated LRRC52-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LRRC52-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRC52-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and THCA show a favorable association.

UVM, LUAD, and BLCA are the cancer types where LRRC52-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.581	0.859	<.001	87	view →
LUAD	DFS	Quartile	II,III,IV	0.794	0.602	.007	39	view →
BLCA	OS	Quartile	All	0.611	0.753	.004	32	view →
THCA	OS	Tertile	All	1.000	0.946	.012	25	view →
CHOL	DFS	Tertile	III,IV	0.133	0.779	.038	15	view →
TGCT	DFS	Quartile	All	0.645	0.915	.003	14	view →
KICH	OS	Median	II,III,IV	1.000	0.887	.009	14	view →
MESO	OS	Tertile	III,IV	0.595	0.347	.034	9	view →
PAAD	OS	Tertile	II,III,IV	0.766	0.539	.015	9	view →
READ	DFS	Tertile	IV	0.397	0.823	.016	9	view →
LUSC	DFS	Median	IV	0.134	0.827	.014	6	view →
LGG	OS	Median	All	0.934	0.857	.019	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

LRRC52-AS1–UVM (DFS)

Open the UVM breakdown →