LRRC49

Across TCGA patient cohorts, LRRC49 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,471 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC49-associated proteins across cancer lineages are HDGFL3, CTSC, and FAM98B. Each is linked with LRRC49 in more than 6 cancer types. Because this analysis shows association rather than direction, both LRRC49-to-partner and partner-to-LRRC49 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC49 versus HDGFL3 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC49→partner) and Y-score (partner→LRRC49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HDGFL3 →	+0.592	+0.749	<.001	<.001	3	7
GBM	CTSC →	-0.538	-0.554	<.001	<.001	3	6
HNSC	FAM98B →	+0.235	+0.615	<.001	<.001	2	7
HNSC	ABI2 →	+0.387	+0.823	<.001	<.001	3	6
BRCA	IFT140 →	+0.586	+0.575	<.001	<.001	3	6
BRCA	IGF1R →	+0.686	+0.653	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,471 associations by consensus.

LRRC49 vs HDGFL3 — HNSC

Explore this scatter interactively →