LRRC46

Across TCGA cell cohorts, LRRC46 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,368 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC46-associated GO terms across cancer lineages are Cilium movement involved in cell motility, Regulation of double-strand break repair, and Flagellated sperm motility. Each is linked with LRRC46 in more than 11 cancer types. Because this analysis shows association rather than direction, both LRRC46-to-partner and partner-to-LRRC46 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium movement involved in cell motility grouped by LRRC46-low versus LRRC46-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC46→partner) and Y-score (partner→LRRC46) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.127	-0.399	<.001	.001	3	12
OESOPHAGUS	Regulation of double-strand break repair →	+0.060	+0.619	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.111	-0.302	<.001	.004	3	11
LIVER	Protein localization to cilium →	+0.050	+0.618	.002	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.111	-0.302	<.001	.004	3	11
STOMACH	mRNA export from nucleus →	+0.121	+0.755	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,368 associations by consensus.

Cilium movement involved in cell motility by LRRC46 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →