LRRC45

Across TCGA patient cohorts, LRRC45 protein abundance is significantly associated with the RNA expression of many other genes, with 6,887 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRRC45-associated genes across cancer lineages are RP1, CFAP94, and DNAH7. Each is linked with LRRC45 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRRC45-to-partner and partner-to-LRRC45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC45 versus RP1 in UCEC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC45→partner) and Y-score (partner→LRRC45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RP1 →	+0.930	+0.356	<.001	<.001	3	4
UCEC	CFAP94 →	+0.827	+0.425	<.001	<.001	3	4
UCEC	DNAH7 →	+1.251	+0.612	<.001	<.001	3	4
UCEC	CCDC170 →	+1.292	+0.474	<.001	<.001	3	4
UCEC	DNAI1 →	+1.633	+0.427	<.001	<.001	3	4
UCEC	RGS22 →	+1.367	+0.507	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,887 associations by consensus.

LRRC45 vs RP1 — UCEC

Explore this scatter interactively →