LRRC42

Across TCGA cell cohorts, LRRC42 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,077 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC42-associated GO terms across cancer lineages are Mitotic spindle organization, Microtubule cytoskeleton organization involved in mitosis, and Regulation of post-translational protein modification. Each is linked with LRRC42 in more than 11 cancer types. Because this analysis shows association rather than direction, both LRRC42-to-partner and partner-to-LRRC42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic spindle organization grouped by LRRC42-low versus LRRC42-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC42→partner) and Y-score (partner→LRRC42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Mitotic spindle organization →	+0.086	+1.279	<.001	<.001	3	12
LARGE_INTESTINE	Microtubule cytoskeleton organization involved in mitosis →	+0.091	+1.080	<.001	<.001	3	12
LARGE_INTESTINE	Regulation of post-translational protein modification →	+0.039	+0.631	<.001	<.001	3	12
SOFT_TISSUE	Spindle elongation →	+0.216	+0.907	.002	<.001	3	11
BREAST	Mitotic spindle midzone assembly →	+0.226	+1.118	<.001	<.001	3	11
LARGE_INTESTINE	Mitotic sister chromatid segregation →	+0.091	+0.920	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,077 associations by consensus.

Mitotic spindle organization by LRRC42 expression — LARGE_INTESTINE

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