LRRC40

Across TCGA cell cohorts, LRRC40 RNA expression is significantly associated with the RNA expression of many other genes, with 9,601 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC40-associated genes across cancer lineages are USP1, SGO2, and XPO1. Each is linked with LRRC40 in more than 19 cancer types. Because this analysis shows association rather than direction, both LRRC40-to-partner and partner-to-LRRC40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC40 versus USP1 in OESOPHAGUS, with a Pearson correlation of 0.81.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC40→partner) and Y-score (partner→LRRC40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	USP1 →	+1.380	+1.234	<.001	<.001	3	20
BLOOD_Myeloma	SGO2 →	+1.278	+1.212	<.001	<.001	3	19
OESOPHAGUS	XPO1 →	+0.917	+0.996	<.001	.001	3	19
PANCREAS	RPF1 →	+1.199	+0.901	<.001	.001	3	18
BLOOD_Myeloma	ATG4C →	+0.923	+0.944	<.001	.002	3	18
OVARY	ORC3 →	+0.991	+0.852	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,601 associations by consensus.

LRRC40 vs USP1 — OESOPHAGUS

Explore this scatter interactively →