LRRC4

Across TCGA patient cohorts, LRRC4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,949 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LRRC4-associated proteins across cancer lineages are CACNA2D1, TBC1D2B, and TCF20. Each is linked with LRRC4 in more than 4 cancer types. Because this analysis shows association rather than direction, both LRRC4-to-partner and partner-to-LRRC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC4 versus CACNA2D1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC4→partner) and Y-score (partner→LRRC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CACNA2D1 →	+0.764	+0.800	<.001	<.001	3	5
UCEC	TBC1D2B →	-0.263	-0.748	.002	.004	3	4
LSCC	TCF20 →	+0.251	+1.016	<.001	<.001	3	4
LSCC	EEPD1_S554 →	+0.603	+0.866	<.001	<.001	3	4
LSCC	GSTM3 →	+1.104	+1.198	<.001	<.001	3	4
LSCC	SEC24A →	-0.325	-1.107	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,949 associations by consensus.

LRRC4 vs CACNA2D1 — GBM

Explore this scatter interactively →