LRRC37BP1

Across TCGA pan-cancer cohorts, LRRC37BP1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated LRRC37BP1 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LRRC37BP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LRRC37BP1 expression acts as an unfavorable survival marker.

UCEC, LUSC, and LUAD are the cancer types where LRRC37BP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.224	0.768	.005	12	view →
LUSC	DFS	Median	II,III,IV	0.135	0.663	.015	12	view →
LUAD	OS	Median	All	0.375	0.700	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

LRRC37BP1–UCEC (OS)

Open the UCEC breakdown →