LRRC37B

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC37B mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC37B-associated genes across cancer lineages are IGFBP2, p62 Lck ligand, and Caspase-7-cleavedD198. Each is linked with LRRC37B in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC37B-to-partner and partner-to-LRRC37B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC37B→partner) and Y-score (partner→LRRC37B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECIGFBP2 →-0.518-2.321.027.03332
UCECp62 Lck ligand →+0.403+1.925<.001.00532
UCECCaspase-7-cleavedD198 →+0.654+1.341.002.04332
UCECc-Met_pY1235 →+0.066+1.710.013.02532
SKCMGAPDH →+0.653+3.169.016.01831
SKCMPI3K-p85 →+0.215+2.820.027.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration