Across TCGA cell cohorts, LRRC37B mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LRRC37B-associated genes across cancer lineages are OR2D3, OR1L6, and OR2J2. Each is linked with LRRC37B in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC37B-to-partner and partner-to-LRRC37B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC37B→partner) and Y-score (partner→LRRC37B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR2D3 →	+0.042	+4.315	<.001	.006	3	2
LARGE_INTESTINE	OR1L6 →	+0.015	+3.700	<.001	.009	3	2
LARGE_INTESTINE	OR2J2 →	+0.013	+3.217	<.001	.006	3	2
BONE	S100A12 →	+0.035	+4.169	<.001	.008	3	1
BONE	RETNLB →	+0.135	+4.169	<.001	.008	3	1
BONE	RNASE11 →	+0.027	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

Exploration

LRRC37B survival (RNA) · tumor vs normal (RNA) · all LRRC37B data types