LRRC37A4P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC37A4P mutation is significantly associated with the RNA expression of many other genes, with 182 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC37A4P-associated genes across cancer lineages are OR4A17P, OPRPN, and OR1N1. Each is linked with LRRC37A4P in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC37A4P-to-partner and partner-to-LRRC37A4P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC37A4P→partner) and Y-score (partner→LRRC37A4P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECOR4A17P →+0.056+3.434.001.00132
BLCAOPRPN →+0.083+4.588<.001.00831
BLCAOR1N1 →+0.123+4.238<.001.00831
BLCAMBD3L2B →+0.675+5.814<.001.00131
BLCARNU6-73P →+0.463+5.618<.001.00231
UCECRNVU1-31 →+0.950+2.780.006.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 182 associations by consensus.

Exploration