LRRC37A2

Across TCGA pan-cancer cohorts, LRRC37A2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated LRRC37A2 data layer compared with 31 for mass-spec protein.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher LRRC37A2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated LRRC37A2 expression acts as an unfavorable survival marker.

PRAD and LIHC are the cancer types where LRRC37A2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
LIHC	DFS	Median	III,IV	0.100	0.363	.025	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

LRRC37A2–PRAD (DFS)

Open the PRAD breakdown →