LRRC31

Across TCGA patient cohorts, LRRC31 RNA expression is significantly associated with the RNA expression of many other genes, with 14,738 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible LRRC31-associated genes across cancer lineages are LRRIQ4, C4orf19, and GK5. Each is linked with LRRC31 in more than 29 cancer types. Because this analysis shows association rather than direction, both LRRC31-to-partner and partner-to-LRRC31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC31 versus LRRIQ4 in ESCA, with a Pearson correlation of 0.79.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC31→partner) and Y-score (partner→LRRC31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	LRRIQ4 →	+1.175	+2.202	<.001	<.001	3	30
ESCA	C4orf19 →	+2.978	+2.300	<.001	<.001	3	22
KICH	GK5 →	+1.049	+1.360	<.001	<.001	3	21
PRAD	FRK →	+1.088	+1.298	<.001	<.001	3	21
ESCA	PBLD →	+1.239	+1.792	<.001	<.001	3	21
ESCA	MYO5C →	+2.086	+1.787	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,738 associations by consensus.

LRRC31 vs LRRIQ4 — ESCA

Explore this scatter interactively →