LRRC31

Across TCGA cell cohorts, LRRC31 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,685 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LRRC31-associated GO terms across cancer lineages are Protein transport within lipid bilayer, Renal D-glucose absorption, and Adenylate cyclase-activating serotonin receptor signaling pathway. Each is linked with LRRC31 in more than 7 cancer types. Because this analysis shows association rather than direction, both LRRC31-to-partner and partner-to-LRRC31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein transport within lipid bilayer grouped by LRRC31-low versus LRRC31-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC31→partner) and Y-score (partner→LRRC31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein transport within lipid bilayer →	+0.314	+1.638	<.001	<.001	3	8
LARGE_INTESTINE	Renal D-glucose absorption →	+1.152	+1.618	<.001	<.001	3	7
BREAST	Adenylate cyclase-activating serotonin receptor signaling pathway →	+0.225	+1.260	<.001	<.001	3	6
STOMACH	Galactolipid biosynthetic process →	+1.267	+1.274	<.001	.002	3	6
STOMACH	Secretion by tissue →	+0.285	+1.622	.003	.002	3	6
PANCREAS	Lateral line system development →	+1.995	+0.770	<.001	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,685 associations by consensus.

Protein transport within lipid bilayer by LRRC31 expression — LARGE_INTESTINE

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