LRRC31

Across TCGA cell cohorts, LRRC31 mutation is significantly associated with the drug of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LRRC31-associated genes across cancer lineages are CP466722, AZD5991, and GSK2256098C. Each is linked with LRRC31 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC31-to-partner and partner-to-LRRC31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CP466722 grouped by LRRC31-low versus LRRC31-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC31→partner) and Y-score (partner→LRRC31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CP466722 →	+0.424	+2.652	.032	.045	3	1
LARGE_INTESTINE	AZD5991 →	+0.900	+2.649	.018	.046	3	1
LARGE_INTESTINE	GSK2256098C →	+0.321	+2.906	.037	.033	3	1
LARGE_INTESTINE	Ispinesib Mesylate →	+0.742	+2.652	.022	.045	3	1
LARGE_INTESTINE	Quizartinib →	+0.397	+2.652	.013	.045	3	1
LARGE_INTESTINE	776928 →	+0.642	+2.649	.042	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

CP466722 by LRRC31 expression — LARGE_INTESTINE

Explore this box plot interactively →