LRRC30

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LRRC30 mutation is significantly associated with the RNA expression of many other genes, with 2,145 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC30-associated genes across cancer lineages are MSANTD3, TIMM21, and RPA3. Each is linked with LRRC30 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRRC30-to-partner and partner-to-LRRC30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC30→partner) and Y-score (partner→LRRC30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMSANTD3 →+0.623+4.332<.001<.00133
UCECTIMM21 →+0.494+2.098.001.00333
UCECRPA3 →+0.521+2.098.001.00333
UCECKCNIP2-AS1 →+0.396+2.628<.001.00533
UCECRN7SL2 →+0.846+2.601.007.00632
UCECRNA5SP414 →+0.538+2.255<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,145 associations by consensus.

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