Across TCGA cell cohorts, LRRC30 RNA expression is significantly associated with the mutation status of many other genes, with 60 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LRRC30-associated genes across cancer lineages are PASK, GGA1, and PLCL1. Each is linked with LRRC30 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC30-to-partner and partner-to-LRRC30 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC30→partner) and Y-score (partner→LRRC30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PASK →	+4.417	+0.475	.004	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	GGA1 →	+4.357	+0.070	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	PLCL1 →	+4.357	+0.070	.006	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	ANKLE2 →	+5.357	+0.093	.003	<.001	3	1
UPPER_AERODIGESTIVE_TRACT	COPG1 →	+4.357	+0.070	.006	<.001	3	1
LUNG_SCLC	TFR2 →	+3.817	+0.091	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

LRRC30 survival (RNA) · tumor vs normal (RNA) · all LRRC30 data types