LRRC28

Across TCGA patient cohorts, LRRC28 protein abundance is significantly associated with the protein abundance of many other proteins, with 718 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LRRC28-associated proteins across cancer lineages are ARL1, CDKL5, and CLIC6_S305. Each is linked with LRRC28 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC28-to-partner and partner-to-LRRC28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC28 versus ARL1 in LSCC, with a Pearson correlation of -0.84.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC28→partner) and Y-score (partner→LRRC28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARL1 →	-0.402	-0.877	.001	.002	3	1
LSCC	CDKL5 →	-0.412	-0.532	<.001	.004	3	1
LSCC	CLIC6_S305 →	+0.609	+0.873	.004	.003	3	1
LSCC	GATA6_S268 →	+0.604	+0.555	<.001	.002	3	1
LSCC	IQSEC1_S160 →	+1.394	+0.612	<.001	<.001	3	1
LSCC	JAG2_S1123 →	+1.138	+0.549	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 718 associations by consensus.

LRRC28 vs ARL1 — LSCC

Explore this scatter interactively →