LRRC27

Across TCGA cell cohorts, LRRC27 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,041 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LRRC27-associated GO terms across cancer lineages are Sperm motility, Cilium or flagellum-dependent cell motility, and Flagellated sperm motility. Each is linked with LRRC27 in more than 15 cancer types. Because this analysis shows association rather than direction, both LRRC27-to-partner and partner-to-LRRC27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by LRRC27-low versus LRRC27-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC27→partner) and Y-score (partner→LRRC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.133	-0.987	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.095	-0.631	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.133	-0.987	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.095	-0.631	<.001	<.001	3	16
LARGE_INTESTINE	Cilium movement involved in cell motility →	-0.110	-1.037	<.001	<.001	3	16
BONE	Transport along microtubule →	+0.051	+1.075	.007	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,041 associations by consensus.

Sperm motility by LRRC27 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →