LRRC27

Across TCGA cell cohorts, LRRC27 protein abundance is significantly associated with the RNA expression of many other genes, with 627 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible LRRC27-associated genes across cancer lineages are MAPK7, FRMD7, and PTGES. Each is linked with LRRC27 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRRC27-to-partner and partner-to-LRRC27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC27 versus MAPK7 in STOMACH, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC27→partner) and Y-score (partner→LRRC27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	MAPK7 →	+1.385	+0.846	.003	<.001	3	4
BLOOD_Myeloma	FRMD7 →	+0.033	+0.822	.002	.004	3	3
STOMACH	PTGES →	-3.844	-0.717	.004	.008	3	3
LUNG_SCLC	ZMAT3 →	-0.953	-0.634	.002	.001	3	3
URINARY_TRACT	DLG2 →	+0.919	+0.753	<.001	<.001	3	3
SKIN	USB1 →	+0.615	+1.156	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 627 associations by consensus.

LRRC27 vs MAPK7 — STOMACH

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