LRRC25

Across TCGA patient cohorts, LRRC25 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRRC25-associated genes across cancer lineages are CD8+ T-cells, CD8+ naive T-cells, and Adipocytes. Each is linked with LRRC25 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRC25-to-partner and partner-to-LRRC25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ T-cells grouped by LRRC25-low versus LRRC25-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC25→partner) and Y-score (partner→LRRC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	CD8+ T-cells →	+0.032	+4.565	.031	.016	3	1
UCEC	CD8+ naive T-cells →	+0.037	+3.016	.006	.019	3	1
UCEC	Adipocytes →	+0.021	+1.922	.017	.027	3	1
SKCM	MEP →	-0.032	-3.138	.030	.020	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CD8+ T-cells by LRRC25 expression — LUSC

Explore this box plot interactively →