LRRC20

Across TCGA cell cohorts, LRRC20 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,115 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LRRC20-associated GO terms across cancer lineages are Nucleosome disassembly, Positive regulation of mitotic cytokinesis, and DNA replication initiation. Each is linked with LRRC20 in more than 10 cancer types. Because this analysis shows association rather than direction, both LRRC20-to-partner and partner-to-LRRC20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleosome disassembly grouped by LRRC20-low versus LRRC20-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC20→partner) and Y-score (partner→LRRC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleosome disassembly →	+0.175	+1.246	.001	<.001	3	11
BLOOD_Myeloma	Positive regulation of mitotic cytokinesis →	+0.149	+1.218	.001	.009	3	11
BLOOD_Myeloma	DNA replication initiation →	+0.144	+1.153	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Deoxyribonucleoside monophosphate biosynthetic process →	+0.196	+1.291	.001	<.001	3	11
BONE	Protein-DNA complex disassembly →	+0.144	+1.149	.004	<.001	2	11
PANCREAS	Spindle elongation →	+0.178	+1.248	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,115 associations by consensus.

Nucleosome disassembly by LRRC20 expression — BONE

Explore this box plot interactively →