LRRC2

Across TCGA patient cohorts, LRRC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,261 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRRC2-associated proteins across cancer lineages are ZAP70, SEPTIN4, and CELF2. Each is linked with LRRC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRC2-to-partner and partner-to-LRRC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRRC2 versus ZAP70 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC2→partner) and Y-score (partner→LRRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZAP70 →	+0.790	+0.299	<.001	.001	3	6
PDAC	SEPTIN4 →	+0.548	+0.377	<.001	<.001	3	6
BRCA	CELF2 →	+0.566	+0.358	<.001	<.001	3	6
HNSC	EPB41L2 →	+0.342	+0.728	.003	.002	3	6
BRCA	ERG_S81 →	+0.699	+0.392	<.001	.001	3	6
HNSC	HSPB6 →	+0.991	+0.887	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,261 associations by consensus.

LRRC2 vs ZAP70 — BRCA

Explore this scatter interactively →