LRRC2

Across TCGA cell cohorts, LRRC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,061 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LRRC2-associated GO terms across cancer lineages are Cellular response to interferon-alpha, Establishment of protein localization to membrane, and Lactam metabolic process. Each is linked with LRRC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LRRC2-to-partner and partner-to-LRRC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to interferon-alpha grouped by LRRC2-low versus LRRC2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRC2→partner) and Y-score (partner→LRRC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cellular response to interferon-alpha →	+0.116	+0.130	<.001	.006	3	6
SOFT_TISSUE	Establishment of protein localization to membrane →	+0.052	+0.409	<.001	.004	3	6
SOFT_TISSUE	Lactam metabolic process →	+1.284	+0.422	<.001	.003	3	5
SOFT_TISSUE	Regulation of protein maturation →	+0.154	+0.408	<.001	.004	3	5
SOFT_TISSUE	Viral life cycle →	+0.101	+0.792	<.001	.002	3	5
LARGE_INTESTINE	Regulation of natural killer cell differentiation →	+0.314	+0.770	.004	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,061 associations by consensus.

Cellular response to interferon-alpha by LRRC2 expression — OVARY

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